Does Additional Use of Preoperative Azithromycin Decrease Posthysterectomy Infections

NARecruitingINTERVENTIONAL
Enrollment

2,278

Participants

Timeline

Start Date

September 5, 2022

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2030

Conditions
Infection Post OpHysterectomyAntibioticsProphylactic
Interventions
DRUG

Azithromycin Pill + Cefuroxime

Azithromycin 500 mg (2 tablets) per orally when arriving to the hospital before the operation and a single dose Cefuroxime 1.5g (when body mass index is under 30) or 3g (for those whose body mass index is 30 or more) in the operating theatre before the incision

DRUG

Placebo + Cefuroxime

Placebo (2 tablets) per orally in the evening when arriving to the hospital before the operation and a single dose Cefuroxime 1.5g (when body mass index is under 30) or 3g (for those whose body mass index is 30 or more) in the operating theatre before the incision

Trial Locations (6)

33521

RECRUITING

Tampere University Central Hospital, Tampere

40620

RECRUITING

Jyväskylä Central Hospital, Jyväskylä

70029

RECRUITING

Kuopio University Central Hospital, Kuopio

Unknown

RECRUITING

Helsinki University Central Hospital, Helsinki

RECRUITING

Turku University Central Hospital, Turku

PL23

RECRUITING

Oulu University Central Hospital, Oulu

All Listed Sponsors
collaborator

University of Turku

OTHER

collaborator

Tampere University Hospital

OTHER

collaborator

Kuopio University Hospital

OTHER

collaborator

Oulu University Hospital

OTHER

collaborator

Jyväskylä Central Hospital

OTHER

lead

Helsinki University Central Hospital

OTHER