NCT05332561View on ClinicalTrials.gov

Genomics Guided Targeted Post-neoadjuvant Therapy in Patients With Early Breast Cancer (COGNITION-GUIDE)

PHASE2RecruitingINTERVENTIONAL
Enrollment

240

Participants

Timeline

Start Date

June 29, 2023

Primary Completion Date

March 31, 2030

Study Completion Date

December 31, 2030

Conditions
Early-stage Breast Cancer
Interventions
DRUG

Atezolizumab 1200 mg in 20 ML Injection

Arm 1

DRUG

Inavolisib

Arm 2

DRUG

Ipatasertib

Arm 3

DRUG

Olaparib

Arm 4

DRUG

Sacituzumab govitecan

Arm 5

DRUG

Trastuzumab/pertuzumab

Arm 6

Trial Locations (9)

45147

NOT_YET_RECRUITING

Universitätsklinikum Essen, Essen

69120

RECRUITING

National Center for Tumor Diseases, Heidelberg

72076

RECRUITING

Universitätsklinikum Tübingen, Tübingen

86156

RECRUITING

Universitätsklinikum Augsburg, Augsburg

89075

RECRUITING

Universitätsklinikum Ulm, Ulm

91054

RECRUITING

Universitätsklinikum Erlangen, Erlangen

97080

NOT_YET_RECRUITING

Universitätsklinikum Würzburg, Würzburg

01397

RECRUITING

Universitätsklinikum Carl-Gustav-Carus, Dresden

Unknown

RECRUITING

Charité - Universitätsmedizin Berlin, Berlin

All Listed Sponsors
lead

German Cancer Research Center

OTHER