NCT05331664View on ClinicalTrials.gov

Dropless Pars Plana Vitrectomy Study

PHASE4RecruitingINTERVENTIONAL
Enrollment

168

Participants

Timeline

Start Date

July 25, 2022

Primary Completion Date

July 25, 2026

Study Completion Date

January 30, 2027

Conditions
Rhegmatogenous Retinal Detachment
Interventions
PROCEDURE

Pars plana vitrectomy

Standard of care surgery

DRUG

Triamcinolone Acetonide 40mg/mL

Sub-tenon injection of triamcinolone acetonide (40mg/mL) at the time of surgery

DRUG

Moxifloxacin 0.5% or Polymyxin/Trimethoprim if patient is allergic to moxifloxacin

Antibiotic eye drop 4 times per day for 1 week after surgery

DRUG

Prednisolone 1%

Steroid eye drop 4 times per day tapered by one drop weekly for 4 weeks (4/3/2/1 taper) after surgery

DRUG

Atropine 1%

Eye drop daily for 1 week after surgery

Trial Locations (1)

02114

RECRUITING

Massachusetts Eye and Ear, Boston

All Listed Sponsors
lead

Massachusetts Eye and Ear Infirmary

OTHER