Glucocorticoids for Post-operative Patients With Acute Type A Aortic Dissection (The GLAD Trial)

PHASE4CompletedINTERVENTIONAL
Enrollment

212

Participants

Timeline

Start Date

February 7, 2022

Primary Completion Date

November 29, 2023

Study Completion Date

November 29, 2023

Conditions
MethylprednisoloneGlucocorticoidAortic DissectionOrgan Dysfunction
Interventions
DRUG

Methylprednisolone Injection

All eligible patients randomised to the glucocorticoid group will receive intravenous Methylprednisolone for 3 days after surgery. The dosage is 2mg/kg/d on post-operative day 1, 1mg/kg/d on post-operative day 2, and 0.5mg/kg/d on post-operative day 3. The daily dosage will be administered with two injections (12h interval).

Trial Locations (1)

200000

Zhongshan Hospital, Shanghai

All Listed Sponsors
lead

Shanghai Zhongshan Hospital

OTHER