Stimulating After Recovery From Traumatic Brain Injury

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

January 15, 2025

Primary Completion Date

January 15, 2028

Study Completion Date

January 15, 2028

Conditions
TBI (Traumatic Brain Injury)
Interventions
COMBINATION_PRODUCT

External non-invasive stimulation

The participants are randomized into the block design of sham or tACS during the first three appointments or the last three appointments. Eye tracking will be used to test the predominant focus of decisions during the gaze phase on costs or difficulty levels during the COGED. The study is investigating the use of neuromodulation after TBI for improved cognitive function.

BEHAVIORAL

COGED

The COGED task consists of the classic N-back task of working memory-based decision making, followed by a valuation phase. The N-back phase of the task allows calculation of cognitive performance of a working memory task. During valuation, participants receive titrating offers of differing amounts of money to perform different difficulty levels of the N-back. The result is an effort discounting curve used to measure the individual effort cost. Effort discounting curves show the perceived cognitive effort required to complete each level of the task relative to another (typically the 1-back).

Trial Locations (1)

55415

RECRUITING

Hennepin County Medical Center, Minneapolis

All Listed Sponsors
collaborator

United States Department of Defense

FED

collaborator

Uniformed Services University of the Health Sciences

FED

lead

University of Minnesota

OTHER