Contact Aspiration Versus Stent Retriever for Recanalisation of Acute Stroke Patients With Basilar Artery Occlusion: The Posterior Circulation ASTER Randomized Trial Protocol

NARecruitingINTERVENTIONAL
Enrollment

480

Participants

Timeline

Start Date

November 19, 2022

Primary Completion Date

July 31, 2026

Study Completion Date

July 31, 2027

Conditions
Basilar Artery Occlusion
Interventions
PROCEDURE

Contact aspiration Thrombectomy

"The contact aspiration approach is performed, as in standard care, using a long sheath positioned in the distal cervical vasculature using an exchange technique.~A large bore balloon guide catheter as to be placed into the cervical ICA. The microcatheter is then advanced close to the thrombus and the large-bore aspiration catheter is advanced as close to the proximal aspect of the thrombus as possible. A control superselective angiogram may be used to document the extent of occlusion and thrombus. After a 3 min waiting period, the large-bore aspiration catheter is connected to a continuous aspiration from the dedicated aspiration pump while simultaneously advancing the aspiration catheter up to the face of the thrombus. through the long sheath positioned in the cervical vasculature."

PROCEDURE

Stent retriever thrombectomy

The technique used should be in accordance with the device IFU. A large bore access guide catheter possible is recommended. A suitable delivery microcatheter is navigated over a microwire across the occlusion. A control superselective angiogram may be used to document the extent of occlusion and thrombus. The stent is left in place according to the internal practice of each participating center before the withdrawal. Any CE-marked stent retriever device is then deployed across the occlusion. A minimum of 3 attempts with SR should be performed. A revascularization score will be recorded after each device attempt.

Trial Locations (12)

Unknown

RECRUITING

Chu Bordeaux, Bordeaux

NOT_YET_RECRUITING

CHU Caen, Caen

NOT_YET_RECRUITING

CHU Limoges, Limoges

NOT_YET_RECRUITING

CHU Montpellier, Montpellier

RECRUITING

Chru Nancy, Nancy

NOT_YET_RECRUITING

Chu Nantes, Nantes

NOT_YET_RECRUITING

APHP - Pitié Salpêtrière, Paris

RECRUITING

Fondation Adolphe de Rothschild, Paris

NOT_YET_RECRUITING

CHU de Reims, Reims

NOT_YET_RECRUITING

CHU Rennes, Rennes

RECRUITING

Hôpital FOCH, Suresnes

NOT_YET_RECRUITING

CHU de Tours, Tours

All Listed Sponsors
lead

Hopital Foch

OTHER