Effectiveness of MR-guided LITT Therapy in Irresectable Glioblastoma (EMITT)

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

238

Participants

Timeline

Start Date

April 8, 2022

Primary Completion Date

October 31, 2025

Study Completion Date

October 31, 2027

Conditions
Primary Glioblastoma
Interventions
PROCEDURE

Laser Interstitial Thermal Therapy (LITT)

LITT is a minimally invasive neurosurgical procedure in which a laser catheter is placed into the tumor and warms the tumor to such an extent that tumor tissue is destroyed. LITT is performed under MR-guidance.

PROCEDURE

Biopsy

A sample of tissue from the tumor is obtained to confirm the diagnosis.

Trial Locations (7)

Unknown

Amsterdam Medical Center, Amsterdam

University Medical Center Groningen, Groningen

Maastricht University Medical Center, Maastricht

Radboud University Medical Center, Nijmegen

Erasmus Medical Center, Rotterdam

Elisabeth Tweesteden Ziekenhuis, Tilburg

University Medical Center Utrecht, Utrecht

All Listed Sponsors
collaborator

Dutch National Health Care Institute

OTHER

collaborator

ZonMw: The Netherlands Organisation for Health Research and Development

OTHER

collaborator

UMC Utrecht

OTHER

lead

Radboud University Medical Center

OTHER