Preoperative Bevacizumab Injection in Primary Pterygium in Tunisian Patients

PHASE4CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

January 1, 2019

Primary Completion Date

January 1, 2021

Study Completion Date

January 1, 2021

Conditions
Pterygium
Interventions
DRUG

Preoperative Intra-lesional Bevacizumab Injection in primary pterygium

"The surgical technique featured:~subconjunctival anesthetic (lidocaine 2%) injection 5 mm from limbus; excision of the pterygium, starting from its head, followed by pterygium body removal; exposition of a triangular-shaped bare scleral bed (3-4 mm) conjunctival autograft stitched limbus to limbus with 10/0 vicryl suture Any intraoperative complication was noted and was treated accordingly. All patients received dexamethasone + tobramycin eye drops postoperatively 4 times a day in the 1st week. The eye drops were tapered over 4 weeks.~Patients were examined 30 days before bevacizumab injection (D-30), before surgery (day 0: D0) and then at D7, M1, M3, and M6 after surgery."

PROCEDURE

pterygium surgery without adjunctive therapy

"The surgical technique featured:~subconjunctival anesthetic (lidocaine 2%) injection 5 mm from limbus; excision of the pterygium, starting from its head, followed by pterygium body removal; exposition of a triangular-shaped bare scleral bed (3-4 mm) conjunctival autograft stitched limbus to limbus with 10/0 vicryl suture"

Trial Locations (1)

2037

Dhouha Gouider, Aryanah

All Listed Sponsors
lead

University Hospital Fattouma Bourguiba

OTHER

NCT05314673 - Preoperative Bevacizumab Injection in Primary Pterygium in Tunisian Patients | Biotech Hunter | Biotech Hunter