NCT05310461View on ClinicalTrials.gov

Early Versus Deferred Aortic Valve Replacement in Patients With Moderate Aortic Stenosis and Mitral Regurgitation

NARecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

August 17, 2022

Primary Completion Date

July 1, 2024

Study Completion Date

January 1, 2030

Conditions
Aortic Valve Replacement in Patients With Moderate Aortic Stenosis Combined With Mitral Regurgitation
Interventions
PROCEDURE

Transcatheter or surgical aortic valve replacement with or without transcatheter or surgical mitral valve repair/replacement

Early transcatheter or surgical aortic valve replacement with or without transcatheter or surgical mitral valve repair/replacement.

PROCEDURE

Deferred treatment, with intervention once AVA is ≤1.0 cm2 or if concomitant mitral regurgitation meets an indication for intervention

Deferred transcatheter or surgical aortic valve replacement with or without transcatheter or surgical mitral valve repair/replacement.

Trial Locations (3)

3010

RECRUITING

Insel Gruppe AG, Inselspital Bern, Bern

Unknown

RECRUITING

University Hospital Geneva (HUG), Geneva

RECRUITING

Heart Clinic Hirslanden, Zurich

All Listed Sponsors
lead

Insel Gruppe AG, University Hospital Bern

OTHER