Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms

NARecruitingINTERVENTIONAL
Enrollment

144

Participants

Timeline

Start Date

April 1, 2022

Primary Completion Date

December 30, 2024

Study Completion Date

January 1, 2028

Conditions
CachexiaNeoplasmsExerciseMetabolismBody CompositionInsulin ResistancePhysical Functional PerformanceQuality of LifeSarcopeniaCaregiversAdipose TissueMuscle, SkeletalPatient Reported Outcome MeasuresGastrointestinal MicrobiomeProteomicsLipidomicsEpigenomicsMitochondria
Interventions
BEHAVIORAL

Exercise training

Patients will be enrolled in a 8 week, supervised, single-leg kicking training intervention (1h, or as long as possible, 60-70% peak workload (PWL), 2-5 days a week). Healthy age-, body weight-, gender- and activity level-matched control subjects will undertake the intervention matched to the %PWL obtained by the patients who complete the study.

Trial Locations (1)

2100

RECRUITING

University of Copenhagen, Copenhagen

All Listed Sponsors
collaborator

Rigshospitalet, Denmark

OTHER

lead

University of Copenhagen

OTHER