Restrictive Versus Liberal Rate of Extracorporeal Volume Removal Evaluation in Acute Kidney Injury

NATerminatedINTERVENTIONAL
Enrollment

99

Participants

Timeline

Start Date

July 5, 2022

Primary Completion Date

June 17, 2024

Study Completion Date

June 26, 2024

Conditions
Acute Kidney InjuryFluid OverloadHypotensionDialysis; ComplicationsCritical Illness
Interventions
PROCEDURE

Restrictive UFnet Rate Strategy

In the restrictive group, the UFnet rate will be titrated between 0.5-1.5 mL/kg/h and maintained throughout fluid removal.

PROCEDURE

Liberal UFnet Rate Strategy

In the liberal group, the UFnet rate will be titrated between 2.0-5.0 mL/kg/h and maintained throughout fluid removal.

Trial Locations (2)

15261

University of Pittsburgh Medical Center, Pittsburgh

55905

Mayo Clinic, Rochester

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Mayo Clinic

OTHER

collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

University of Pittsburgh

OTHER

NCT05306964 - Restrictive Versus Liberal Rate of Extracorporeal Volume Removal Evaluation in Acute Kidney Injury | Biotech Hunter | Biotech Hunter