Exploration of GCase Activity to Identify a Subpopulation Eligible for a Therapeutic Trial in Dementia with Lewy Bodies

RecruitingOBSERVATIONAL

Enrollment

236

Participants

Timeline

Start Date

February 17, 2023

Primary Completion Date

June 30, 2025

Study Completion Date

June 30, 2025

Conditions

Dementia with Lewy Bodies

Interventions

DIAGNOSTIC_TEST

Glucocerebrosidase

Blood sample (10ml) for GCase activity

GENETIC

GBA gene

Blood sample (10ml) for variants or mutations of the GBA gene

DIAGNOSTIC_TEST

Macrophage biomarkers

Blood sample (20ml) for macrophage biomarkers

Trial Locations (1)

RECRUITING

Centre de neurologie Cognitive, Paris

All Listed Sponsors

lead

Assistance Publique - Hôpitaux de Paris

OTHER