Usefulness of Integrated PET/MRI in Oropharyngeal Squamous Cell Carcinoma Evaluation

CompletedOBSERVATIONAL
Enrollment

233

Participants

Timeline

Start Date

August 1, 2015

Primary Completion Date

October 31, 2018

Study Completion Date

December 31, 2021

Conditions
Oropharyngeal Cancer
Interventions
DIAGNOSTIC_TEST

PETMRI

PET/MRI data will be acquired on the integrated PET/MRI scanner. After fast-view T1-weighted MR localizer sequence for scout imaging and Dixon VIBE sequence for attenuation correction, a whole-body PET scan will be performed to cover from the head to the proximal thigh, with an acquisition time of 4 min per bed position. Simultaneously, whole body MR image acquisition will be performed with the axial HASTE sequence and coronal STIR sequence as well as the sagittal T1-weighted Turbo spine echo and STIR sequence. Afterwards, regional PET and MRI images will be simultaneously performed. DWI will be performed using a single shot spin-echo echo-planar technique. A total of 10 b values will be used for the reconstruction of IVIM and kurtosis imaging. DCE-PWI will be acquired by using a 3D T1-weighted spoiled gradient-echo sequence. Thereafter, dedicated regional MRI will be obtained. Finally, whole body axial VIBE with fat saturation will be performed.

Trial Locations (1)

333

Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Guishan

All Listed Sponsors
lead

Chang Gung Memorial Hospital

OTHER

NCT05299957 - Usefulness of Integrated PET/MRI in Oropharyngeal Squamous Cell Carcinoma Evaluation | Biotech Hunter | Biotech Hunter