PRotein Optimization With eXercise to Improve MUscle Mass and Functional outcomeS

NARecruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

February 20, 2023

Primary Completion Date

December 1, 2025

Study Completion Date

June 30, 2026

Conditions
Muscle LossProteinMobilityPediatric ALL
Interventions
OTHER

Protein dosage and rehabilitation team delivered exercise prescription

"The dietitian and rehabilitation team will be consulted on enrollment and will assess the patient for nutritional and functional status using the institutional criteria and physical exam. The study dietitian will prescribe the protein goal based on the randomization assignment and age group. For the high protein arm, protein goals will be 3g/kg/day for ages 1-1yrs, and 2.4g/kg/day for ages greater than 12 years.~The rehabilitation team will determine the appropriate highest level of mobility (HLM) for the day in collaboration with the medical team on morning rounds. The rehabilitation team will prescribe passive or active participation in two 30-minute HLM sessions, individualized to their baseline function and clinical status and/or restrictions."

Trial Locations (2)

21218

RECRUITING

Johns Hopkins Hospital, Baltimore

02115

RECRUITING

Boston Children's Hospital, Boston

All Listed Sponsors
collaborator

Johns Hopkins University

OTHER

lead

Boston Children's Hospital

OTHER