Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

240

Participants

Timeline

Start Date

April 14, 2022

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
KRAS P.G12CNon-small Cell Lung CancerColorectal CancerPancreatic Ductal Carcinoma
Interventions
DRUG

JAB-21822

KRAS G12C inhibitor

DRUG

JAB-3312

SHP2 inhibitor

Trial Locations (27)

100005

NOT_YET_RECRUITING

Pecking Union Medical College Hospital, Beijing

100021

RECRUITING

Cancer Hospital Chinese Academy Of Medical Sciences, Beijing

100070

NOT_YET_RECRUITING

Beijing Tiantan Hospital, Captal Medical University, Beijing

100142

RECRUITING

Beijing Cancer Hospital, Beijing

100191

RECRUITING

Peking University Third Hospital, Beijing

101125

NOT_YET_RECRUITING

Beijing Chest Hospital, Capital Medical University, Beijing

110001

NOT_YET_RECRUITING

The First Hospital Of China Medical University, Shenyang

150081

NOT_YET_RECRUITING

Harbin Medical University Cancer Hospital-Mammary gland of internal, Harbin

200032

NOT_YET_RECRUITING

Fudan University Shanghai Cancer Center, Shanghai

230001

NOT_YET_RECRUITING

The First Affiliated Hospital of USTC Anhui Provincial Hospital, Hefei

250012

NOT_YET_RECRUITING

Qilu Hospital of Shandong University, Jinan

250117

NOT_YET_RECRUITING

Shandong Cancer Hospital, Jinan

276002

NOT_YET_RECRUITING

LinYi Cancer Hospital, Linyi

310009

NOT_YET_RECRUITING

The Second Affiliated Hospital Zhejiang School of Medicine, Hangzhou

350014

NOT_YET_RECRUITING

Fujian cancer Hospital, Fuzhou

361003

NOT_YET_RECRUITING

The First Affiliated Hospital Xiamen University, Xiamen

410008

NOT_YET_RECRUITING

Xiangya Hospital Central South Univesity, Changsha

410031

NOT_YET_RECRUITING

Hunan Cancer Hospital, Changsha

430022

NOT_YET_RECRUITING

Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan

430030

NOT_YET_RECRUITING

Tongji Hospital Tongji Medical College of Hust, Wuhan

430060

NOT_YET_RECRUITING

Renmin Hospital Of Wuhan University, Wuhan

450003

NOT_YET_RECRUITING

Henan Cancer Hospital, Zhengzhou

450052

NOT_YET_RECRUITING

The First Affiliated Hosipital Of Zhengzhou University, Zhengzhou

510080

NOT_YET_RECRUITING

The first Affiliated Hospital, Sun Yat-sen University, Guangzhou

510280

NOT_YET_RECRUITING

Zhujiang Hospital of Southem Medical University, Guangzhou

518116

NOT_YET_RECRUITING

Cancer Hospital Chinese Academy Of medical Sciences Shenzhen Center, Shenzhen

750306

NOT_YET_RECRUITING

The Affilated Hospital of Inner Mongolia Medical University, Hohhot

Sponsors
All Listed Sponsors
lead

Allist Pharmaceuticals, Inc.

INDUSTRY