Critical Illness Myopathy and Trajectory of Recovery in AKI Requiring CRRT

Active, not recruitingOBSERVATIONAL
Enrollment

10

Participants

Timeline

Start Date

November 29, 2021

Primary Completion Date

September 30, 2023

Study Completion Date

December 30, 2024

Conditions
Acute Kidney InjuryCritical Illness MyopathyDialysis; Complications
Interventions
DIAGNOSTIC_TEST

Musculoskeletal ultrasound

Ultrasound of rectus femoris to determine cross-sectional area, muscle thickness, echo intensity.

DIAGNOSTIC_TEST

Assessments of muscle strength and physical function

A battery of tests of physical function and muscle strength (see outcomes section for details).

DIAGNOSTIC_TEST

Metabolomics

Using metabolomic analysis, concentrations of amino acids and other important analytes will be measured in patient plasma and CRRT effluent

Trial Locations (3)

40506

University of Kentucky, Lexington

52242

University of Iowa, Iowa City

87106

University of New Mexico, Albuquerque

All Listed Sponsors
lead

University of Iowa

OTHER