Rheolytic Thrombectomy For Acute Deep Vein Thrombosis Of Whole Lower Limb

NARecruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

September 1, 2022

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2027

Conditions
Deep Vein Thrombosis
Interventions
DEVICE

pharmacomechanical thrombectomy (PMT)

After randomization patients will be allocated to pharmacomechanical thrombectomy (PMT) via ipsilateral popliteal venous approach or to PMT via distal calf venous approach, bail-out contralateral femoral access can be used if puncture was failed in calf vein. After PMT treatment, residual thrombus was reevaluated by ascending venography. Catheter-directed thrombolysis (CDT) was conducted if there was residual thrombus. Stenosis of iliac vein was assessed by multiangle venography and intravascular ultrasound (IVUS) was used if necessary. Percutaneous balloon angioplasty (PTA) was conducted if there was \>50% stenosis of the diameter of the iliac vein. A stent was placed if the residual stenosis was \>50% after PTA treatment.

Trial Locations (1)

200127

RECRUITING

Renji Hospital, Shanghai

All Listed Sponsors
collaborator

First People's Hospital of Hangzhou

OTHER

collaborator

The First Affiliated Hospital with Nanjing Medical University

OTHER

collaborator

Affiliated Hospital of Nantong University

OTHER

collaborator

Chengdu University of Traditional Chinese Medicine

OTHER

collaborator

Second Affiliated Hospital of Suzhou University

OTHER

collaborator

Liuzhou Workers' Hospital

OTHER_GOV

collaborator

Shanghai Pudong New Area People's Hospital

OTHER

collaborator

Zhejiang University

OTHER

lead

RenJi Hospital

OTHER