nCCR for Chemotherapy Related Cognitive Impairment Randomized Study

NAActive, not recruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

August 1, 2022

Primary Completion Date

June 1, 2028

Study Completion Date

March 1, 2029

Conditions
Chemo-brainChemotherapy-Related Cognitive Impairment
Interventions
BEHAVIORAL

Neuroplasticity-based Computerized Cognitive Remediation

"Behavioral: Neuroplasticity-based Computerized Cognitive Remediation The nCCR has two major components: Bottom up and Top down training.~* Bottom up training: The training includes selected tasks from Brain HQ, a program designed for older adults, that enhances basic processing of sensory stimuli with the goal to improve fidelity of auditory and visual encoding.~* Top down training: We designed programs to target cognitive control functions associated with poor treatment response, i.e., initiation and use of verbal strategy and susceptibility to interference. These Top Down Programs include a visual attention program, either Catch the Ball or Neurogrow, and a semantic strategy program, Semantic Organization."

BEHAVIORAL

Education Control Condition

The education control condition is a learning-based approach that utilizes DVDs on history, art, science, etc. This active condition is comparable to nCCR in length of exposure, audio-visual presentation, computer use and contact with research staff.

Trial Locations (1)

37212

Center for Cognitive Medicine at Vanderbilt University, Nashville

All Listed Sponsors
collaborator

University of Utah

OTHER

lead

Vanderbilt University Medical Center

OTHER