A Multi-domain Approach for the Characterization and Early Diagnosis of Neurodevelopmental Disorders

NACompletedINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

March 1, 2016

Primary Completion Date

May 31, 2021

Study Completion Date

May 31, 2021

Conditions
Neurodevelopmental Disorders
Interventions
DIAGNOSTIC_TEST

EEG

resting state EEG

DIAGNOSTIC_TEST

DNA samples

genotypings of twelve CNTNAP2 SNPs from DNA obtained by saliva samples

DIAGNOSTIC_TEST

clinical data

"standardized scales measuring the infants' cognitive, motor and linguistic development administered at 6, 12 and 18. Measures available at 6 and 12 months: a) Bayley Scales of Infant and Toddler Development- Third Edition; b) Griffiths mental development scales (0-2) (GMDS-R); Measures available at 18 months: c) Language Development Survey (LDS); d) Il PRIMO VOCABOLARIO DEL BAMBINO (PVB); e) CHILD BEHAVIOR CHECKLIST (CBCL); (f) Modified Checklist for Autism in Toddlers (M-CHAT)."

OTHER

environmental data

questionnaires administered to parents related to the following environmental factors: a) information about the presence of a clinical diagnosis of neurodevelopmental disorders within first-degree relatives; b) gestational age; c) birth weight; d) parental age and education; e) socio-economic status

Trial Locations (1)

23842

Scientific Institute IRCCS E. Medea, Bosisio Parini

All Listed Sponsors
collaborator

Ministry of Health, Italy

OTHER_GOV

lead

IRCCS Eugenio Medea

OTHER

NCT05269927 - A Multi-domain Approach for the Characterization and Early Diagnosis of Neurodevelopmental Disorders | Biotech Hunter | Biotech Hunter