Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

500

Participants

Timeline

Start Date

June 14, 2022

Primary Completion Date

May 15, 2027

Study Completion Date

August 31, 2027

Conditions
Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)
Interventions
DRUG

Anakinra

See information in arm/group descriptions

DRUG

Placebo

See information in arm/group descriptions

Trial Locations (32)

15260

RECRUITING

Children's Hospital of Pittsburgh, Pittsburgh

17033

RECRUITING

Pennsylvania State University, Hershey

19104

RECRUITING

Children's Hospital of Philadelphia, Philadelphia

20010

RECRUITING

Children's National Medical Center, Washington D.C.

23298

RECRUITING

Virginia Commonwealth University, Richmond

27705

RECRUITING

Duke University, Durham

29425

RECRUITING

Medical University of South Carolina, Charleston

30329

RECRUITING

Children's Hospital of Atlanta, Atlanta

35233

RECRUITING

Children's of Alabama, Birmingham

43205

RECRUITING

Nationwide Children's Hospital, Columbus

44106

RECRUITING

Rainbow Babies and Children's Hospital, Cleveland

44308

RECRUITING

Akron Children's Hospital, Akron

45229

RECRUITING

Cincinnati Children's Hospital Medical Center, Cincinnati

46204

RECRUITING

Riley Children's Hospital, Indianapolis

48109

RECRUITING

CS Mott Children's Hospital, Ann Arbor

48201

RECRUITING

Children's Hospital of Michigan, Detroit

53233

NOT_YET_RECRUITING

Medical College of Wisconsin, Milwaukee

55404

NOT_YET_RECRUITING

Children's Hospital of Minnesota, Minneapolis

55455

RECRUITING

University of Minnesota, Minneapolis

64108

RECRUITING

Mercy Children's Hospital, Kansas City

64609

RECRUITING

Benioff Children's Hospital - Oakland, Oakland

72202

RECRUITING

Arkansas Children's Hospital, Little Rock

75390

RECRUITING

University of Texas Southwestern, Dallas

77030

RECRUITING

Texas Children's Hospital, Houston

78207

RECRUITING

Children's Hospital of San Antonio, San Antonio

80045

RECRUITING

Children's Hospital Colorado, Aurora

84158

RECRUITING

Primary Children's Hospital, Salt Lake City

90027

RECRUITING

Children's Hospital of Los Angeles, Los Angeles

92123

RECRUITING

Rady Children's Hospital, San Diego

92868

NOT_YET_RECRUITING

Children's Hospital of Orange County, Orange

94143

RECRUITING

Benioff Children's Hospital - Mission Bay, San Francisco

95817

RECRUITING

University of California, Davis, Sacramento

All Listed Sponsors
collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

Nationwide Children's Hospital

OTHER