A Phase 2/3 Study of Efgartigimod PH20 SC in Adult Participants With Bullous Pemphigoid

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

98

Participants

Timeline

Start Date

June 9, 2022

Primary Completion Date

September 13, 2024

Study Completion Date

September 13, 2024

Conditions
Bullous Pemphigoid
Interventions
BIOLOGICAL

efgartigimod PH20 SC

Subcutaneous injection of efgartigimod coformulated with rHuPH20, a permeation enhancer

OTHER

placebo

Subcutaneous injection of placebo coformulated with rHuPH20, a permeation enhancer

DRUG

Prednisone

Oral Prednisone

Trial Locations (129)

1001

Investigator site 87 - LV3710005, Riga

1003

Investigator site 82 - LV3710003, Riga

Investigator site 88 - LV3710004, Riga

1085

Investigator site 26 - HU0360023, Budapest

1407

Investigator site 28 - BG3590018, Sofia

1431

Investigator site 14 - BG3590010, Sofia

2217

Investigator site 27 - AU0610006, Kogarah

3065

Investigator site 36 - AU0610013, Fitzroy

4032

Investigator site 11 - HU0360003, Debrecen

4102

Investigator site 125 - AU0610019, Woolloongabba

6003

Investigator site 15 - BG3590020, Stara Zagora

7632

Investigator site 7 - HU0360008, Pécs

9713

Investigator site 66 - NL0310015, Groningen

10000

Investigator site 16 - HR3850002, Zagreb

Investigator site 37 - HR3850001, Zagreb

10016

Investigator site 93 - US0010169, New York

10117

Investigator site 46 - DE0490039, Berlin

11040

Investigator site 84 - RS3810010, Belgrade

11525

Investigator site 60 - GE0300004, Athens

Investigator site 62 - GE0300006, Athens

12462

Investigator site 76 - GR030003, Chaïdári

14203

Investigator site 5 - US0010088, Buffalo

15213

Investigator site 25 - US0010158, Pittsburgh

16121

Investigator site 58 - GR0300001, Athens

16132

Investigator site 81 - IT0390030, Genova

18000

Investigator site 67 - RS3810012, Niš

18016

Investigator site 8 - ES0340053, Granada

20122

Investigator site 77 - IT0390062, Milan

21000

Investigator site 22 - HR3850003, Split

Investigator site 69 - RS3810009, Novi Sad

24105

Investigator site 56 - DE0490028, Kiel

25132

Investigator site 43 - IT0390060, Brescia

26505

Investigator site 3 - US0010151, Morgantown

27100

Investigator site 64 - IT0390061, Pavia

28034

Investigator site 12 - ES0340025, Madrid

28041

Investigator 20 - ES0340029, Madrid

29009

Investigator site 31 - ES0340057, Málaga

33173

Investigator site 1 - US0010017, Miami

33428

Investigator site 2 - US0010087, Boca Raton

33611

Investigator site 48 - ES0340059, Mieres

33756

Investigator site 21 - US0010152, Clearwater

35043

Investigator site 45 - DE0490001, Marburg

35055

Investigator site 79 - PL0480025, Rzeszów

39216

Investigator site 115 - US0010157, Jackson

40138

Investigator site 65 - IT0390055, Bologna

40217

Investigator site 35 - US0010156, Louisville

40225

Investigator site 80 - DE0490041, Düsseldorf

41009

Investigator site 9 - ES0340052, Seville

43126

Investigator site 119 - IT0390066, Parma

45147

Investigator site 51 - DE0490008, Essen

45324

Investigator site 4 - US0010137, Fairborn

46017

Investigator site 70 - ES0340061, Valencia

46940

Investigator site 49 - ES0340058, Manises

47906

Investigator site 13 - US0010155, West Lafayette

48109

Investigator site 50 - US0010149, Ann Arbor

50122

Investigator site 47 - IT0390031, Florence

Investigator site 86 - IT0390067, Florence

53100

Investigator site 30 - IT0390040, Siena

54643

Investigator site 61 - GE0300002, Thessaloniki

56429

Investigator site 59 - GR0300005, Thessaloniki

60590

Investigator site 52 - DE0490024, Frankfurt am Main

63110

Investigator site 73 - US0010098, St Louis

64239

Investigator site 40 - IL9720002, Tel Aviv

76031

Investigator site 29 - FR0330029, Rouen

77004

Investigator site 34 - US0010182, Houston

79104

Investigator site 53 - DE0490023, Freiburg im Breisgau

80109

Investigator site 10 - US0010153, Castle Rock

84107

Investigator site 92 - US0010150, Murray

85006

Investigator site 74 - US0010178, Phoenix

Investigator site 75 - DE0490047, München

90404

Investigator site 72 - US0010186, Santa Monica

91054

Investigator site 57 - DE0490046, Erlangen

91702

Investigator site 114 - SK4210003, Trnava

92708

Investigator site 6 - US0010138, Fountain Valley

94063

Investigator site 121 - US0010092, Redwood City

95123

Investigator site 78 - IT0390039, Catania

97080

Investigator site 55 - DE0490026, Würzburg

100006

Investigator site 111 - CN0860064, Beijing

110000

Investigator 68 - RS381011, Belgrade

200025

Investigator site 127 - CN860020, Shanghai

200435

Investigator site 123 - CN0860095, Shanghai

330000

Investigator site 124 - CN0860098, Nanchang

350004

Investigator site 108 - CN0860023, Fujian

400006

Investigator site 90 - RO0400014, Cluj-Napoca

400016

Investigator site 116 - CN0860027, Chongqing

430031

Investigator site 109 - CN0860025, Wuhan

450003

Investigator site 126 - CN0860026, Zhengzhou

510080

Investigator site 110 - CN0860053, Guanzhou

510091

Investigator site 107 - CN0860021, Guangzhou

700111

Investigator site 89 - RO0400015, Iași

830054

Investigator site 122 - CN0860065, Ürümqi

1834111

Investigator site 39 - IL9720003, Afula

3109601

Investigator site 63 - IL9720018, Haifa

4210002

Investigator site 113 - SK4210002, Bratislava

5262100

Investigator site 41 - IL9720001, Ramat Gan

03756

Investigator site 85 - US0010159, Lebanon

Unknown

Investigator site 91 - CN0860017, Beijing

Investigator site 95 - CN0860018, Chengdu

Investigator site 128 - CN0860097, Hefei

Investigator site 94 - CN0860066, Nanyang

Investigator site 71 - UK0440036, London

656 91

Investigator site 97 - CZ4200015, Brno

500 05

Investigator site 118 - CZ4200016, Hradec Králové

13, 301 00

Investigator site 117 - CZ4200013, Plzen-Bory

180 81

Investigator site 96 - CZ4200012, Prague

06202

Investigator site 38 - FR0330040, Nice

01307

Investigator site 54 - DE0490030, Dresden

00167

Investigator site 23 - IT0390006, Roma

00168

Investigator site 42 - IT0390005, Roma

860-8556

Investigator site 103 - JP0810070, Kumamoto

830-0011

Investigator site 99 - JP0810050, Kurume

371-8511

Investigator site 104 - JP0810071, Maebashi

480-1195

Investigator site 100 - JP0810046, Nagakute

951-8520

Investigator site 129 - JP0810073, Niigata

545-8586

Investigator site 101 - JP0810049, Osaka

589-8511

Investigator site 102 - JP0810069, Ōsaka-sayama

060-8648

Investigator site 112 - JP0810045, Sapporo

980-8574

Investigator site 105 - JP0810067, Sendai

113-8431

Investigator site 98 - JP0810043, Tokyo

236-0004

Investigator site 106 - JP0810068, Yokohama

90-647

Investigator site 17 - PL0480047, Lodz

00-716

Investigator site 83 - PL0480050, Warsaw

50-220

Investigator site 18 - PL0480048, Wroclaw

51-685

Investigator site 19 - PL0480046, Wroclaw

040 11

Investigator site 120 - SK4210004, Košice

08916

Investigator site 32 - ES0340050, Badalona

08003

Investigator 24 - ES0340051, Barcelona

BS2 8HW

Investigator site 33 - UK0440022, Bristol

SO16 6YD

Investigator site 44 - UK0440037, Southampton

Sponsors

Lead Sponsor

All Listed Sponsors
lead

argenx

INDUSTRY