NCT05259917 - A Phase III, Crossover Trial Evaluating the Efficacy and Safety of KVD900 (Sebetralstat) for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE) | Biotech Hunter

Enrollment

136

Participants

Timeline

Start Date

February 22, 2022

Primary Completion Date

December 31, 2023

Study Completion Date

December 31, 2023

Conditions

Hereditary Angioedema

Interventions

DRUG

Placebo

Placebo to KVD900 Tablet

DRUG

KVD900 600 mg

KVD900 Tablet 600 mg (2 x 300 mg)

DRUG

KVD900 300 mg

KVD900 Tablet 300 mg (1 x 300 mg)

Trial Locations (66)

1000

KalVista Investigative Site, Skopje

1023

KalVista Investigative Site, Auckland

1088

KalVista Investigative Site, Budapest

1431

KalVista Investigative Site, Sofia

2560

KalVista Investigative Site, Campbelltown

10029

KalVista Investigative Site, New York

11521

Kalvista Investigative Site, Athens

11527

KalVista Investigative Site, Athens

12203

KalVista Investigative Site, Berlin

17033

KalVista Investigative Site, Hershey

20097

KalVista Investigative Site, San Donato Milanese

20815

KalVista Investigative Site, Chevy Chase

28046

KalVista Investigative Site, Madrid

28277

KalVista Investigative Site, Charlotte

31048

KalVista Investigative Site, Haifa

33613

KalVista Investigative Site, Tampa

35128

KalVista Investigative Site, Padua

35209

KalVista Investigative Site, Birmingham

38043

KalVista Investigative Site, Grenoble

40215

KalVista Investigative Site, Louisville

43617

KalVista Investigative Site, Toledo

49202

KalVista Investigative Site, Petach Tikvah

52621

KalVista Investigative Site, Ramat Gan

55131

KalVista Investigative Site, Mainz

55446

KalVista Investigative Site, Plymouth

59000

KalVista Investigative Site, Lille

59037

KalVista Investigative Site, Lille

60590

KalVista Investigative Site, Frankfurt am Main

60612

KalVista Investigative Site, Chicago

61414

KalVista Investigative Site, St Louis

64239

KalVista Investigative Site, Tel Aviv

64546

KalVista Investigative Site, Mörfelden-Walldorf

66211

KalVista Investigative Site, Overland Park

72205

KalVista Investigative Site, Little Rock

75231

KalVista Investigative Site, Dallas

75571

KalVista Investigative Site, Paris

80112

KalVista Investigative Site, Centennial

80907

KalVista Investigative Site, Colorado Springs

84041

KalVista Investigative Site, Layton

85251

KalVista Investigative Site, Scottsdale

90404

KalVista Investigative Site, Santa Monica

92122

KalVista Investigative Site, San Diego

92123

KalVista Investigative Site, San Diego

99202

KalVista Investigative Site, Spokane

547530

KalVista Investigative Site, Sângeorgiu de Mureş

M3B 3S6

KalVista Investigative Site, Toronto

569-8686

KalVista Investgative Site, Takatsuki-shi

260-8677

KalVista Investgative Site, Chiba

371-8511

KalVista Investigative Site, Gunma

730-8518

KalVista Investigative Site, Hiroshima

340-0041

KalVista Investigative Site, Saitama

236-0004

KalVista Investigative Site, Yokohama

1105 AZ

KalVista Investigative Site, Amsterdam

15-276

KalVista Investigative Site, Bialystok

31-503

KalVista Investigative Site, Krakow

92-213

KalVista Investigative Site, Lodz

4200-319

KalVista Investigative Site, Porto

00918

KalVista Investigative Site, San Juan

03659

KalVista Investigative Site, Martin

08035

KalVista Investigative Site, Barcelona

08907

KalVista Investigative Site, Barcelona

B9 5SS

KalVista Investigative Site, Birmingham

CF14 4XW

KalVista Investigative Site, Cardiff

GU16 7UJ

KalVista Investigative Site, Frimley

LS9 7TF

KalVista Investigative Site, Leeds

E1 1FR

KalVista Investigative Site, London