NCT05257447View on ClinicalTrials.gov

Pharmacokinetic and Bioequivalence Comparison of Baclofen and Chlorzoxazone Administered Individually or Concurrently

PHASE1CompletedINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

April 27, 2022

Primary Completion Date

December 13, 2022

Study Completion Date

December 13, 2022

Conditions
Pharmacokinetics
Interventions
DRUG

Baclofen 20 mg Tablet

Single oral dose given at approximately 8 AM on day of visit, with 6-8 ounces of tap water.

DRUG

Chlorzoxazone 500 mg Tablet

Single oral dose given at approximately 8 AM on day of visit, with 6-8 ounces of tap water.

DRUG

Baclofen 20mg tablet and Chlorzoxazone 500 mg tablet

Concurrent single oral dose given at approximately 8 AM on day of visit, with 6-8 ounces of tap water.

Trial Locations (1)

75390

UT Southwestern Medical Center, Dallas

All Listed Sponsors
collaborator

Tufts University

OTHER

lead

University of Texas Southwestern Medical Center

OTHER