Study of Sotorasib Combined With Chemotherapy for Second Line Treatment of Pancreas Cancer

PHASE1/PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

September 13, 2022

Primary Completion Date

January 31, 2023

Study Completion Date

January 31, 2023

Conditions
Pancreatic CancerUnresectable Pancreatic CancerMetastatic Pancreatic CancerKRAS P.G12C
Interventions
DRUG

Sotorasib

Intervention instruction outlined in protocol

DRUG

Liposomal Irinotecan (nal-IRI)

Intervention instruction outlined in protocol

DRUG

5 Fluorouracil (5FU)

Per standard of care

DRUG

Leucovorin (LV)

Per standard of care

DRUG

Gemcitabine (GEM)

Per standard of care

DRUG

Nab paclitaxel

Per standard of care

Trial Locations (1)

60611

Northwestern University, Chicago

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Amgen

INDUSTRY

lead

Devalingam Mahalingam

OTHER

NCT05251038 - Study of Sotorasib Combined With Chemotherapy for Second Line Treatment of Pancreas Cancer | Biotech Hunter | Biotech Hunter