BOLD MRI and FMISO PET for the Assessment of Hypoxic Tumor Microenvironment in Patients with Oligometastatic Liver Cancer Undergoing Yttirum-90 Selective Internal Radiation Therapy

EARLY_PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

April 28, 2022

Primary Completion Date

February 26, 2025

Study Completion Date

February 26, 2025

Conditions

BCLC Stage a Hepatocellular CarcinomaBCLC Stage B Hepatocellular CarcinomaBCLC Stage C Hepatocellular CarcinomaHepatocellular Carcinoma

Interventions

OTHER

18F-Fluoromisonidazole

Given IV

PROCEDURE

Biopsy

Undergo biopsy

PROCEDURE

Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Undergo DCE MRI

PROCEDURE

Positron Emission Tomography

Undergo PET

Trial Locations (1)

Emory University Hospital/Winship Cancer Institute, Atlanta

All Listed Sponsors

collaborator

National Cancer Institute (NCI)

NIH

lead

Emory University

OTHER