ComPAS Low-WAZ RCT Mali

PHASE2/PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

1,500

Participants

Timeline

Start Date

September 1, 2022

Primary Completion Date

December 31, 2023

Study Completion Date

April 30, 2024

Conditions
Acute Malnutrition in InfancyAcute Malnutrition in ChildhoodUnderweight
Interventions
DIETARY_SUPPLEMENT

Simplified dose of ready-to-use therapeutic food (RUTF)

"In the simplified arm all children receive the same dose: 1 sachet of RUTF/day. This until discharge from treatment.~Recovery from treatment will be defined as WAZ\>= -3 on 2 consecutive visits. A maximum of 12 treatment weeks are allowed before declaring non-response. Defaulting will be declared after 2 consecutively missed visits."

DIETARY_SUPPLEMENT

Standard dose of ready-to-use therapeutic food (RUTF)

"In the standard arm, children will receive different doses of RUTF depending on their WHZ category and weight.~1. children with a WHZ\<-3 will receive the equivalent of 200kcal/kg/d of RUTF until discharge.~2. children with a WHZ between -3 and -2 will receive 1 sachet (500kcal) of RUTF per day until discharge.~3. children with a WHZ\>=-2 will receive no nutritional treatment.~Recovery from treatment will be defined as WHZ\>= -2 on 2 consecutive visits. A maximum of 12 treatment weeks are allowed before declaring non-response. Defaulting will be declared after 2 consecutively missed visits."

DIETARY_SUPPLEMENT

No nutritional treatment

no nutritional treatment will be provided to children in the control arm.

Trial Locations (11)

Unknown

Dilly, Nara

Gassambarou, Nara

Goumbou, Nara

Kaloumba, Nara

Karfabougou, Nara

Koira, Nara

Koronga, Nara

Madina-Kagoro, Nara

Nara Central, Nara

Sampaga, Nara

Tiapato, Nara

Sponsors
All Listed Sponsors
collaborator

University of the Sciences, Techniques and Technologies of Bamako

OTHER

collaborator

Ministry of health, Mali

UNKNOWN

lead

International Rescue Committee

OTHER