Trial to Study the Effect of CVL-231 on 24-Hour Ambulatory Blood Pressure in Participants With Schizophrenia

PHASE1CompletedINTERVENTIONAL
Enrollment

151

Participants

Timeline

Start Date

January 24, 2022

Primary Completion Date

October 19, 2022

Study Completion Date

November 14, 2022

Conditions
Blood PressureSchizophrenia
Interventions
DRUG

CVL-231

CVL-231 is a brain penetrant mAChR activator that selectively binds to the M4 mAChR subtype while sparing other muscarinic receptor subtypes (M1, M2, M3, and M5). CVL-231 is being developed for treatment of psychosis in schizophrenia.

Trial Locations (10)

33016

Innovative Clinical Research, Inc - ClinEdge - PPDS, Miami

44720

Neuro-Behavioral Clinical Research, Inc., North Canton

60640

Uptown Research Institute LLC, Chicago

60712

Pillar Clinical Research LLC, Lincolnwood

72211

Woodland International Research Group LLC - ERG - PPDS, Little Rock

72712

Pillar Clinical Research LLC, Bentonville

75080

Pillar Clinical Research LLC, Richardson

78754

Community Clinical Research, Austin

90806

Collaborative NeuroScience Research, LLC - Torrance - Apex - PPDS, Long Beach

08053

Hassman Research Institute - Apex - PPDS, Marlton

Sponsors
All Listed Sponsors
lead

Cerevel Therapeutics, LLC

INDUSTRY

NCT05245539 - Trial to Study the Effect of CVL-231 on 24-Hour Ambulatory Blood Pressure in Participants With Schizophrenia | Biotech Hunter | Biotech Hunter