The Effects of Subanesthetic S-ketamine on Postoperative Delirium and Cognitive Function in the Elderly Undergoing Non-cardiac Thoracic Surgery

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

520

Participants

Timeline

Start Date

March 10, 2022

Primary Completion Date

August 31, 2025

Study Completion Date

August 31, 2025

Conditions
Postoperative DeliriumElderly Patients
Interventions
DRUG

S-ketamine

Loading dose: 0.25mg/kg in 10 minutes Maintenance dose: 0.1mg/kg/h

DRUG

Dexmedetomidine

Loading dose: 0.2 ug/kg in 10 minutes Maintenance dose: 0.2 ug/kg/h

Trial Locations (1)

510095

Cancer hospital and institute of Guangzhou medical university, Guangzhou

All Listed Sponsors
lead

Affiliated Cancer Hospital & Institute of Guangzhou Medical University

OTHER

NCT05242692 - The Effects of Subanesthetic S-ketamine on Postoperative Delirium and Cognitive Function in the Elderly Undergoing Non-cardiac Thoracic Surgery | Biotech Hunter | Biotech Hunter