Safety and Preliminary Efficacy of IVMED-80 Eye Drops in Keratoconus Patients

Good Manufacturing Practices-grade copper (ІІ) sulfate pentahydrate (CuSO4 #5H2O MW 249.69) was dissolved in a vehicle solution comprised of a balanced salt solution (BSS) with osmolality of approximately 500 mOsm/L. Copper sulfate was concentrated to 0.15 mg/mL. The drops were manufactured on prior to the study at a compounding pharmacy in Salt Lake City, Utah.

This was identical to the IVMED-80 product, but without the active ingredient, copper sulfate.