ERP to Improve Functioning in Veterans With OCD

NARecruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

October 3, 2022

Primary Completion Date

October 31, 2025

Study Completion Date

May 31, 2026

Conditions
Obsessive Compulsive Disorder (OCD)Comorbid Post-Traumatic Stress Disorder and OCD
Interventions
BEHAVIORAL

Exposure and Response Prevention

ERP is a specialized cognitive behavioral intervention conducted over the course of 8-16 therapy sessions. ERP is based upon exposure principles and the idea that people can habituate to the distress caused by OCD triggers and learn to cope with anxiety about feared consequences without engaging in compulsive behaviors to 'neutralize' the obsession. ERP begins with psychoeducation about OCD and exposure, followed by construction of a hierarchy, or list, of situations that are feared, avoided, or trigger OCD rituals such as washing or checking. Then, the therapist and client begin in-session exposures to hierarchy items utilizing response or ritual prevention techniques to avoid reinforcing the ritual. Exposures can be in vivo, such as touching a contaminated item, or imaginal, such as visualizing a feared consequence happening.

OTHER

Stress Management Training

The stress management training intervention will be based on that delivered by Simpson in an ERP trial. It will be delivered by PhD and Master's level therapists from each site's clinics. The stress management training intervention will begin with an introductory session providing psychoeducation about OCD, followed by 15 sessions covering stress management skills such as deep breathing progressive muscle relaxation, positive imagery, assertiveness training, and problem solving. Each session will contain an extended practice of the selected skill and will end with homework assignments to practice the stress management skills and monitor symptoms.

Trial Locations (18)

23667

RECRUITING

Hampton VA Medical Center, Hampton, VA, Hampton

28144

RECRUITING

Salisbury W.G. (Bill) Hefner VA Medical Center, Salisbury, NC, Salisbury

97471

RECRUITING

VA Roseburg Healthcare System, Roseburg, OR, Roseburg

97503

RECRUITING

VA Southern Oregon Rehabilitation Center and Clinics, White City, OR, White City

07018

RECRUITING

East Orange Campus of the VA New Jersey Health Care System, East Orange, NJ, East Orange

14215-1129

RECRUITING

VA Western New York Healthcare System, Buffalo, NY, Buffalo

10010-5011

RECRUITING

VA NY Harbor Healthcare System, New York, NY, New York

11768-2200

RECRUITING

Northport VA Medical Center, Northport, NY, Northport

10468-3904

RECRUITING

James J. Peters VA Medical Center, Bronx, NY, The Bronx

28805-2576

RECRUITING

Asheville VA Medical Center, Asheville, NC, Asheville

27705-3875

RECRUITING

Durham VA Medical Center, Durham, NC, Durham

28301-3856

RECRUITING

Fayetteville VA Medical Center, Fayetteville, NC, Fayetteville

29401-5703

RECRUITING

Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston

77030-4211

RECRUITING

Michael E. DeBakey VA Medical Center, Houston, TX, Houston

23249-0001

RECRUITING

Hunter Holmes McGuire VA Medical Center, Richmond, VA, Richmond

24153-6404

RECRUITING

Salem VA Medical Center, Salem, VA, Salem

99205-6185

RECRUITING

Spokane VA Medical Center, Spokane, WA, Spokane

99362-3975

RECRUITING

Jonathan M. Wainwright Memorial VA Medical Center, Walla Walla, WA, Walla Walla

All Listed Sponsors
lead

VA Office of Research and Development

FED