A Study of Orelabrutinib Plus R-CHOP in Treatment-naïve Patients With MCD Subtype Diffuse Large B-cell Lymphoma

PHASE3RecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

November 2, 2022

Primary Completion Date

July 30, 2024

Study Completion Date

December 30, 2025

Conditions
Diffuse Large B Cell Lymphoma (DLBCL)
Interventions
DRUG

Orelabrutinib + R-CHOP

The orelabrutinib is a white, round, uncoated tablet. The R-CHOP include rituximab, cyclophosphamide, doxorubicin, vincristine, and prednison.

DRUG

Placebo + R-CHOP

The placebo is a white, round, uncoated tablet. The R-CHOP include rituximab, cyclophosphamide, doxorubicin, vincristine, and prednison.

Trial Locations (44)

100730

RECRUITING

Beijing Hospital, Beijing

110002

RECRUITING

The First Hospital of China Medical University, Shenyang

116023

RECRUITING

The Second Hospital of Dalian Medical University, Dalian

200003

ACTIVE_NOT_RECRUITING

Shanghai Changzheng Hospital, Shanghai

200025

RECRUITING

Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai

201306

ACTIVE_NOT_RECRUITING

Shanghai 6th People's Hospital, Shanghai

210008

RECRUITING

The Affiliated Hospital of Nanjing University Medical School, Nanjing

214043

RECRUITING

Wuxi People's Hospital, Wuxi

230031

RECRUITING

Anhui Provincal Cancer Hospital, Hefei

233000

RECRUITING

The first affiliated hospital of bengbu medical college, Bengbu

250000

RECRUITING

Qilu Hospital Of Shandong University, Jinan

250021

RECRUITING

Provincial Hospital Affiliated to Shandong First Medical University, Jinan

266400

RECRUITING

The Affiliated Hospital of Qingdao University, Qingdao

300060

RECRUITING

Tianjin Cancer Hospital, Tianjin

310003

RECRUITING

The first affiliated Hospital Zhejiang University School Of Medicine, Hangzhou

310016

RECRUITING

Sir Run Run Shaw Hospital Zhejiang University School Of Medicine, Hangzhou

312000

RECRUITING

Shaoxing People's Hospital, Shaoxing

330001

RECRUITING

Jiangxi Cancer Hospital, Nanchang

330006

RECRUITING

The First Affiliated Hospital Of Nanchang University, Nanchang

350001

RECRUITING

Fujian Medical University Union Hospital, Fuzhou

361003

RECRUITING

The First Affiliated Hospital Of XIAMEN University, Xiamen

400000

RECRUITING

Chongqing University Cancer Hospital, Chongqing

RECRUITING

The Southwest Hospital of AMU, Chongqing

410011

RECRUITING

The Second Xiangya Hospital of Central South University, Changsha

410013

RECRUITING

Hunan Cancer Hospital, Changsha

423099

RECRUITING

Chenzhou first people's Hospital, Chenzhou

430023

RECRUITING

Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan

430030

RECRUITING

Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan

450008

RECRUITING

Henan Cancer Hospital, Zhengzhou

450052

RECRUITING

The First Affiliated Hospital of Henan University of science and Technology, Luoyang

RECRUITING

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

510060

RECRUITING

Sun Yat-sen University Cancer Center Internal medicine department, Guandong

510180

RECRUITING

Guangdong General Hospital, Guangzhou

510280

RECRUITING

ZhuJiang Hospital of Southern Medical University, Guangzhou

510700

RECRUITING

Sun Yat-sen University Cancer Center, Guangzhou

518036

RECRUITING

PEKING University SHENZHEN Hospital, Shenzhen

528000

RECRUITING

The First People's Hospital of Foshan, Foshan

610000

ACTIVE_NOT_RECRUITING

West China Hospital Sichuan University, Chengdu

710004

ACTIVE_NOT_RECRUITING

The first Affiliated Hospital Of Xi'an Jiaotong University, Xi’an

RECRUITING

The Second Affiliated Hospital Of Xi'an Jiaotong University, Xi’an

730050

RECRUITING

Gansu Provincial Cancer Hospital, Lanzhou

830000

RECRUITING

Affiliated Cancer Hospital of Xinjiang Medical University, Ürümqi

050031

RECRUITING

Affiliated Hospital of Hebei University, Baoding

050000

RECRUITING

The Second Hospital of Hebei Medical University, Shijiazhuang

All Listed Sponsors
lead

Beijing InnoCare Pharma Tech Co., Ltd.

INDUSTRY