NCT05232578View on ClinicalTrials.gov

Early Salvage Therapy for Patients With Advanced Features for Biochemical Relapse After Radical Prostatectomy for Localized Prostate Carcinoma In Correlation With Supposed Molecular-genetic Parameters of Higher Aggressiveness

PHASE3Not yet recruitingINTERVENTIONAL

Enrollment

380

Participants

Timeline

Start Date

September 30, 2022

Primary Completion Date

December 31, 2032

Study Completion Date

December 31, 2032

Conditions

Prostate Cancer

Interventions

RADIATION

Early salvage radiotherapy (eSRT)

"eSRT administered immediately after the confirmation of the biochemical relapse (PSA ≈ 0.2ng/ml).~66-70Gy will be delivered to the bed of prostate. Radiotherapy will be optionally accompanied by androgen deprivation therapy."

RADIATION

Delayed Salvage radiotherapy (dSRT)

"dSRT administered if PSA levels increase to ≥ 0.4 ng/ml.~66-70Gy will be delivered to the bed of prostate. Radiotherapy will be optionally accompanied by androgen deprivation therapy."

All Listed Sponsors

lead

General University Hospital, Prague

OTHER