NCT05227833View on ClinicalTrials.gov

Vonoprazan Efficacy to Prevent Post Variceal Band Ligation Ulcer

PHASE3CompletedINTERVENTIONAL
Enrollment

284

Participants

Timeline

Start Date

February 15, 2022

Primary Completion Date

November 15, 2022

Study Completion Date

November 15, 2022

Conditions
Portal HypertensionVariceal HemorrhageUlcer Hemorrhage
Interventions
DRUG

Vonoprazan fumarate (Vonaspire)

Patients assigned to Vonoprazan (vonaspire) tablets will receive a daily dose of 20 mg before breakfast starting from the first day of band ligation.

DRUG

Pantoprazole 40mg

Patients assigned to Pantoprazole tablets (Controloc OR Antopral OR Perloc) will receive a daily dose of 40 mg before breakfast starting from the first day of band ligation.

OTHER

Placebo

No Intervention

Trial Locations (1)

21521

Alexandria Main University Hospital, Alexandria

All Listed Sponsors
collaborator

Alexandria University Hospital, Alexandria, Alexandria Governorate, Egypt

UNKNOWN

lead

Alexandria University

OTHER