NCT05227300View on ClinicalTrials.gov

Buffered vs. Unbuffered Local Anesthesia in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis

PHASE4CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

February 14, 2022

Primary Completion Date

May 23, 2022

Study Completion Date

June 30, 2022

Conditions
Symptomatic Irreversible Pulpitis
Interventions
DRUG

Onset Sodium Bicarbonate Inj., 8.4%, USP Neutralizing Additive Solution

Onpharma's Onset sodium bicarbonate buffer to be added to a standard cartridge of dental local anesthetic

DRUG

2% lidocaine with 1:100,000 epinephrine

Septodont's standard formulation of 2% lidocaine with epinephrine

Trial Locations (1)

46202

Indiana University School of Dentistry Graduate Endodontics Dept., Indianapolis

All Listed Sponsors
lead

Indiana University

OTHER