The Effect of Intracameral Carbachol and Epinephrine on Choroidal Thickness

NACompletedINTERVENTIONAL
Enrollment

81

Participants

Timeline

Start Date

January 1, 2021

Primary Completion Date

August 30, 2021

Study Completion Date

December 30, 2021

Conditions
Epinephrine ToxicityCataractCarbachol Adverse ReactionChoroid Disease
Interventions
PROCEDURE

Intracameral administration of epinephrine and carbachol during cataract surgery

All surgeries were performed by the same surgeon using a similar technique, under topical anesthesia (0.05% proparacaine HCL), and with a 2.8 mm temporal clear corneal incision. After making the incision, 0.2 mL of preservative-free epinephrine (1:5000) was injected into the epinephrine group only. After complete hydrodissection, the nucleus was removed using the stop and chop technique. Phacoemulsification time (range: 30-60 s) was similar in all patients, while the phacoemulsification strength was set to 35%-40% for all operations. The cortex was aspirated. Before implanting a one-piece foldable hydrophobic acrylic intraocular lens (IOL) into the capsular bag, 1% sodium hyaluronate (ophthalmic viscosurgical device, Healon) was injected into the capsular bag. After removal of the viscoelastic material, only the carbachol group was given 0.5 ml of 0.01% carbachol solution intracamerally. Hydration with balanced salt solution was used to close the corneal incisions.

Trial Locations (1)

52200

Ordu University, Ordu

All Listed Sponsors
lead

T.C. ORDU ÜNİVERSİTESİ

OTHER

NCT05225597 - The Effect of Intracameral Carbachol and Epinephrine on Choroidal Thickness | Biotech Hunter | Biotech Hunter