Interpretation Bias as a Mechanism of Treatment Response in OCD

NARecruitingINTERVENTIONAL
Enrollment

106

Participants

Timeline

Start Date

March 30, 2022

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2026

Conditions
Obsessive-Compulsive Disorder
Interventions
BEHAVIORAL

Cognitive bias modification for interpretation bias

Sessions of scenario-based CBM-I training for OCD will be administered, based on the widely-used paradigm of ambiguous scenario training developed by Mathews and Mackintosh (2000), in which participants are presented with scenarios that are ambiguous in whether or not they are threatening. Participants will complete a computer task consisting of a series of written scenarios designed to improve interpretation and attributional biases; these scenarios conclude with word fragments, which participants must fill in to resolve the ambiguity.

BEHAVIORAL

Psychoeducation

Sessions of psychoeducation will be administered, which will describe symptoms of anxiety, the nature of biased thinking in anxiety, and summarize common psychosocial as well as pharmacological treatments for anxiety. The sessions will provide relevant information but will not provide training in changing thinking styles.

Trial Locations (1)

02478

RECRUITING

McLean Hospital, Belmont

All Listed Sponsors
lead

Mclean Hospital

OTHER