Optimization of PEEP During Laparoscopic Surgery

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

April 14, 2021

Primary Completion Date

December 29, 2023

Study Completion Date

March 26, 2024

Conditions
Post-Op ComplicationVentilator-Induced Lung Injury
Interventions
DIAGNOSTIC_TEST

Respiratory monitoring

Measurement of the plateau pressure, positive end-expiratory pressure, driving pressure, end-expiratory lung volume, compliance of respiratory system on volume-controlled ventilation

DIAGNOSTIC_TEST

Capnography

Measurement of end-tidal carbon dioxide tension, volume of CO2 eliminated per minute

DIAGNOSTIC_TEST

Arterial blood gas

Measurement of the oxygen partial pressure and the carbon dioxide partial pressure

DEVICE

Esophageal pressure

Measurement the pressure in the lower third of esophagus during inspiration and expiration

Trial Locations (1)

010000

National Research Oncology and Transplantology Centre, Astana

All Listed Sponsors
collaborator

I.M. Sechenov First Moscow State Medical University

OTHER

collaborator

National Research Oncology and Transplantology Center, Kazakhstan

OTHER

lead

Karaganda Medical University

OTHER