Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

Regional forearm blockade of β-adrenergic receptors at 20 mcg/dL/min via brachial artery catheter during normoxia and hypoxia exposures

Dose response (1, 3, 6, and 12 ng/dL/min) regional infusion to assess β-adrenergic receptor responsiveness

This infusion will be for 10 min before baseline measurement (12 mcg/dL/min) and continue the infusion at a maintenance rate (5 mcg/dL/min).

Regional forearm infusion at 8 ng/dL/min via brachial artery catheter during normoxia and hypoxia exposures