24
Participants
Start Date
March 9, 2023
Primary Completion Date
April 1, 2026
Study Completion Date
December 31, 2026
Disulfiram
"To be taken orally (PO) daily in the AM, rounded for pill size (max 480mg/day).~To be administered day 1-7 of lead-in week and day 1-28 cycles~Cycle length: 28 days,~maximum 12 cycles Level -1 (150mg/m\^2/day) Level~0 (225mg/m\^2/day) Level 1 (300mg/m\^2/day), max~480mg/day"
Copper Gluconate
"To be taken orally (PO), 5.2mg/m2/day daily in the PM, rounded~for pill size (max 9mg/day) To be administered day 1-7~Lead-in week and day 1-28 cycles Cycle length: 28~days, maximum 12 cycles"
Liposomal Doxorubicin (Doxil)
"To be given IV, 30mg/m2/dose~To be administered day 1 of cycles~Cycle length: 28 days, maximum 12 cycles"
RECRUITING
Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland
Case Comprehensive Cancer Center
OTHER