Standard vs Intensive Rehabilitation and Nutrition Regimen for Inpatients at the ICU

NARecruitingINTERVENTIONAL
Enrollment

500

Participants

Timeline

Start Date

March 10, 2022

Primary Completion Date

January 31, 2024

Study Completion Date

December 31, 2025

Conditions
Nutrition Disorders
Interventions
PROCEDURE

More intensive rehabilitation

Patient exercises with physiotherapists, staff assists with normal activities during the day, activation, and mobilization in and out of bed according to the patient's ability.

DIETARY_SUPPLEMENT

More intensive nutrition

"in addition, the patient will be administered hydroxymethylbutyrate at a dose of 3 g/day - in case of ONS indication (oral nutrition support, formerly sipping) in this form (Ensure advance plus 2 times a day), in case of non-indication or impossibility or intolerance of this form then in the form of a food supplement (Myotec HMB). The minimum total dose delivered is 12 g/5 days.~* in case of hypovitaminosis D and serum Ca concentration up to 3.0 mmol/l, vitamin D will be administered at a dose of 3000 IU/day - cumulative 15000 IU/5 days (missing dose can be given at the end of the cycle in one dose)~* inclusion of probiotics in standard doses"

Trial Locations (1)

70852

RECRUITING

University Hospital Ostrava, Ostrava

All Listed Sponsors
lead

University Hospital Ostrava

OTHER