TOtal Skin Electron Beam Therapy (Low-dose) for Tumor Clone Eradication in Early-stage Mycosis Fungoides

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

78

Participants

Timeline

Start Date

February 28, 2022

Primary Completion Date

February 28, 2027

Study Completion Date

February 28, 2031

Conditions
Mycosis FungoidesCutaneous T Cell Lymphoma
Interventions
OTHER

Low-dose total-skin electron-beam therapy

Low-dose total skin electron beam therapy (12 Gy) will be delivered to the patient in 4 Gy/week, 1 Gy/day over 3 weeks by symmetrical electron beams of 6 MeV energy via a linac accelerator.

OTHER

Phototherapy

"Phototherapy will be given 3 times a week during 2 months, then twice a week during one month, then once a week during one month, or until disease progression or unacceptable side effect, whatever comes first.~Patients with plaques will receive PUVA therapy and patients with patches only will receive narrow-band UVB therapy."

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER