Efficacy of Mesalazine Combined With Biologics in the Treatment of Moderate to Severe Ulcerative Colitis

PHASE4RecruitingINTERVENTIONAL
Enrollment

438

Participants

Timeline

Start Date

January 15, 2022

Primary Completion Date

January 15, 2024

Study Completion Date

January 15, 2025

Conditions
Ulcerative ColitisEfficacy, SelfBiologicsMesalazine
Interventions
DRUG

Infliximab

Infliximab, 5mg/kg at week 0,2,6 and schedule administration at every 8 weeks

DRUG

Vedolizumab

Vedolizumab, 300mg at week 0,2,6 and schedule administration at every 8 weeks

DRUG

Mesalazine

Mesalazine, 4-6g/d, systemic and/or topical administration

Trial Locations (11)

501655

RECRUITING

the Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou

Unknown

NOT_YET_RECRUITING

People's Hospital of Chongqing, Chongqing

RECRUITING

First People's Hospital of Foshan, Guangzhou

RECRUITING

Guangzhou Panyu Central Hospital, Guangzhou

RECRUITING

Nanhai Hospital, Southern Medical University, Guangzhou

RECRUITING

Shunde Hospital of Southern Medical University, Guangzhou

RECRUITING

First Affiliated Hospital of Shantou University Medical College, Shantou

NOT_YET_RECRUITING

The Second Affiliated Hospital of Dalian Medical University, Dalian

RECRUITING

Shengjing Hospital, Shenyang

RECRUITING

General Hospital of Tianjin Medical University, Tianjin

NOT_YET_RECRUITING

Zhejiang University, Hanzhou

All Listed Sponsors
lead

Sixth Affiliated Hospital, Sun Yat-sen University

OTHER

NCT05205603 - Efficacy of Mesalazine Combined With Biologics in the Treatment of Moderate to Severe Ulcerative Colitis | Biotech Hunter | Biotech Hunter