Application of Iced Normal Saline Combined With Cocktail Perfusion in Total Knee Arthroplasty

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

March 2, 2018

Primary Completion Date

June 1, 2018

Study Completion Date

August 1, 2018

Conditions
Pain, PostoperativeBlood Loss, Postoperative
Interventions
DRUG

iced normal saline

Iced normal saline (20ml) was given intraoperative joint cavity infusion therapy

DRUG

Tranexamic acid injection

20ml of tranexamic was given with iced normal saline for intraoperative joint cavity infusion.

OTHER

Cocktail (composing by Ropivacaine, Morphine and Epinephrine) perfusion

Cocktail was formulated during the operation by mixing Ropivacaine 150mg, Morphine 10mg and Epinephrine 1mg, then normal saline was used to dilute the mixture to 60ml. Then the cocktail mixture was applied for the joint cavity perfusion.

Trial Locations (1)

264000

Yantai Yuhuangding Hospital, Yantai

All Listed Sponsors
lead

Yantai Yuhuangding Hospital

OTHER

NCT05204056 - Application of Iced Normal Saline Combined With Cocktail Perfusion in Total Knee Arthroplasty | Biotech Hunter | Biotech Hunter