NCT05203822View on ClinicalTrials.gov

Tepotinib Drug-Drug Interaction Study With Itraconazole in Healthy Participants

PHASE1CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

January 21, 2022

Primary Completion Date

July 5, 2022

Study Completion Date

July 5, 2022

Conditions
Healthy
Interventions
DRUG

Tepotinib (HydroChloride hydrate)

Participants received Tepotinib (Hydrochloride hydrate) Film-coated tablet with food on Day 1 and 12 in the morning.

DRUG

Itraconazole

Participants received Itraconazole Hard-gelatin capsule with food once daily at the same time in the morning from Day 8 to Day 18; on Day 12 itraconazole is administered concomitantly with tepotinib.

Trial Locations (1)

Unknown

Nuvisan GmbH, Neu-Ulm

All Listed Sponsors
lead

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

INDUSTRY