VIBRANT: VIB4920 for Active Lupus Nephritis

PHASE2RecruitingINTERVENTIONAL
Enrollment

74

Participants

Timeline

Start Date

May 16, 2022

Primary Completion Date

August 31, 2026

Study Completion Date

March 31, 2027

Conditions
Lupus Nephritis
Interventions
DRUG

VIB4920

Participants will receive 1500 mg of VIB4920 at Weeks 0, 2, 4, 8, 12, 16, 20, and 24 while continuing on MMF and prednisone

DRUG

Placebo for VIB4920

Participants will receive placebo for VIB4920 at Weeks 0, 2, 4, 8, 12, 16, 20, and 24 while continuing on MMF and prednisone

Trial Locations (17)

10021

NOT_YET_RECRUITING

Hospital for Special Surgery, New York: Division of Rheumatology, New York

10032

RECRUITING

Columbia University Medical Center: Department of Medicine, Division of Rheumatology, New York

11030

RECRUITING

Feinstein Institute for Medical Research: Center for Autoimmune and Musculoskeletal Diseases, Manhasset

17033

NOT_YET_RECRUITING

Penn State Health Milton S. Hershey Medical Center: Division of Rheumatology, Hershey

19140

NOT_YET_RECRUITING

Temple University, Lewis Katz School of Medicine, Department of Medicine: Nephrology, Philadelphia

29425

RECRUITING

University of South Carolina, Charleston

30307

RECRUITING

Emory University School of Medicine: Division of Rheumatology, Atlanta

33136

RECRUITING

University of Miami Miller School of Medicine: Nephrology & Hypertension Division, Miami

43201

NOT_YET_RECRUITING

Ohio State University, Columbus

60637

RECRUITING

University of Chicago, Department of Medicine: Rheumatology, Chicago

63110

RECRUITING

Washington University School of Medicine in St. Louis: Division of Nephrology, St Louis

80045

RECRUITING

University of Colorado School of Medicine: Division of Rheumatology, Aurora

90095

NOT_YET_RECRUITING

UCLA Medical Center: Division of Rheumatology, Los Angeles

92093

NOT_YET_RECRUITING

University of California San Diego School of Medicine: Division of Rheumatology, Allergy and Immunology, La Jolla

92868

NOT_YET_RECRUITING

University of California, Irvine School of Medicine Division of Rheumatology, Orange

94143

RECRUITING

University of California San Francisco School of Medicine: Lupus Clinic and Rheumatology Clinical Research Center, San Francisco

06519

RECRUITING

Yale University School of Medicine: Section of Rheumatology, New Haven

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT05201469 - VIBRANT: VIB4920 for Active Lupus Nephritis | Biotech Hunter | Biotech Hunter