NCT05201066 - Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab. | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

February 13, 2023

Primary Completion Date

February 14, 2028

Study Completion Date

February 14, 2028

Conditions

Myelodysplastic SyndromesLeukemia, Myelomonocytic, Chronic

Interventions

DRUG

decitabine

Solution for intravenous infusion

DRUG

spartalizumab

Solution for intravenous infusion

DRUG

sabatolimab

Solution for intravenous infusion

DRUG

azacitidine

Solution for subcutaneous injection or intravenous infusion

DRUG

venetoclax

Tablet for oral administration

DRUG

INQOVI (oral decitabine)

Tablet for oral administration. HMA = azactidine or decitabine INQOVI = decitabine (oral)

Trial Locations (24)

3168

Novartis Investigative Site, Clayton

8091

Novartis Investigative Site, Zurich

16132

Novartis Investigative Site, Genova

20162

Novartis Investigative Site, Milan

25123

Novartis Investigative Site, Brescia

28009

Novartis Investigative Site, Madrid

31059

Novartis Investigative Site, Toulouse

35100

Novartis Investigative Site, Izmir

50134

Novartis Investigative Site, Florence

59100

Novartis Investigative Site, Kuala Lumpur

79106

Novartis Investigative Site, Freiburg im Breisgau

97239

Oregon Health Sciences University, Portland

130021

Novartis Investigative Site, Changchun

300020

Novartis Investigative Site, Tianjin

84112 0550

Huntsman Cancer Institute Univ of Utah, Salt Lake City

88020-210

Novartis Investigative Site, Florianópolis

V5Z 1M9

Novartis Investigative Site, Vancouver

128 08

Novartis Investigative Site, Prague

681 00

Novartis Investigative Site, Alexandroupoli

265 04

Novartis Investigative Site, Pátrai

00133

Novartis Investigative Site, Roma

960 1295

Novartis Investigative Site, Fukushima

08916

Novartis Investigative Site, Badalona

08036

Novartis Investigative Site, Barcelona