Study of SIAN Nasal Spray in Healthy Adults

PHASE1CompletedINTERVENTIONAL
Enrollment

47

Participants

Timeline

Start Date

December 21, 2021

Primary Completion Date

September 29, 2023

Study Completion Date

October 13, 2023

Conditions
Cyanide Poisoning
Interventions
DRUG

Stabilized Isoamyl Nitrite (SIAN)

"SIAN is comprised of isoamyl nitrite (IAN) stabilized with 4% by weight epoxidized linseed oil (ELSO) and administered by intranasal (IN) delivery as a nasal spray.~A syringe-based spray device will be used to administer the SIAN product. This syringe-based spray device, consists of a Hamilton type syringe connected to a tip that functions as an atomizer, to provide an optimal spray plume for nasal absorption while minimizing exposure to lungs."

Trial Locations (2)

37920

Alliance for Multispecialty Research, LLC, Knoxville

78744

Austin Clinical Research Unit - PPD Phase I Clinic, Austin

Sponsors
All Listed Sponsors
collaborator

Biomedical Advanced Research and Development Authority

FED

lead

Emergent BioSolutions

INDUSTRY