Neural Mechanisms of Imaginal and in Vivo Exposure

NACompletedINTERVENTIONAL
Enrollment

87

Participants

Timeline

Start Date

April 7, 2022

Primary Completion Date

March 1, 2023

Study Completion Date

March 1, 2023

Conditions
Fear of Spiders
Interventions
BEHAVIORAL

Imaginal exposure

Session 1 (Day 1): Participants receive repeated exposure to mental imagery of fear-provoking stimuli (spiders) and neutral stimuli (leaves) while undergoing brain imaging med fMRI.

BEHAVIORAL

Exposure

Session 2 (Ca one week): Participants receive both imaginal and in vivo exposure to fear-provoking stimuli and neutral stimuli (both arms are exposed to both video clips (in vivo exposure) and mental imagery (imaginal exposure). Session 2 is conducted in the laboratory, i.e., no brain imaging.

BEHAVIORAL

Approach-avoidance conflict

Session 2 (Ca one week): Spider fear is probed by an approach-avoidance conflict task. Participants can receive varying small rewards for watching pictures of spiders, or avoid the spider pictures at the cost of not receiving a reward (neutral pictures are shown instead).

BEHAVIORAL

In vivo exposure

Session 1 (Day 1): in vivo exposure. Participants receive repeated exposure to film clips of fear-provoking stimuli (spiders) and neutral stimuli (leaves) while undergoing brain imaging med fMRI.

Trial Locations (1)

22242

The Swedish 7T facility, Lund

All Listed Sponsors
lead

Uppsala University

OTHER