Albumin-Bound Paclitaxel Combined With Antiangiogenic Agents in First-line Treatment of Relapsed or Metastatic TNBC

PHASE2RecruitingINTERVENTIONAL
Enrollment

128

Participants

Timeline

Start Date

January 14, 2022

Primary Completion Date

September 10, 2025

Study Completion Date

December 1, 2025

Conditions
Triple-negative Breast Cancer
Interventions
DRUG

Albumin-Bound Paclitaxel

Albumin-bound paclitaxel is one of the standard first-line regimens for relapsed or metastatic triple-negative breast cancer.

DRUG

Apatinib Mesylate

Apatinib mesylate is an orally administered small-molecule vascular endothelial growth factor receptor-2 (VEGFR-2) tyrosine kinase inhibitor (TKI).

DRUG

Bevacizumab

Bevacizumab is a humanized anti-VEGF monoclonal antibody once approved by FDA for treatment of metastatic breast cancer in combination with chemotherapy.

Trial Locations (1)

233004

RECRUITING

Department of Medical Oncology, First Affiliated Hospital of Bengbu Medical College, Bengbu

All Listed Sponsors
lead

The First Affiliated Hospital of Bengbu Medical University

OTHER