Enhancing the Efficiency of EMLA Cream in Palatal Anesthesia for Children

NACompletedINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

May 20, 2021

Primary Completion Date

August 23, 2021

Study Completion Date

September 27, 2021

Conditions
Extrusion of Tooth
Interventions
OTHER

Conventional local palatine injection

Conventional palatal injection with anesthetic (lidocaine HCL2% with Epinephrine 1:80000, Korea) Then the palatal probe will be performed with a dental probe in contact with the bone to estimate anesthetic effectiveness

DRUG

EMLA cream only

Emla cream will be applied at a distance of 1 mm from the palatine gingival edge by cotton buds for 3 minutes within the application area 14\*14 mm and the mouth will be open throughout the procedure and the saliva will be controlled by a saliva absorbent. Then the palatal probe will be performed with a dental probe in contact with the bone to estimate anesthetic effectiveness.

DRUG

chemical permeability enhancer DMSO with EMLA cream

Adding 10 g of EMLA cream 5%, 1,026 g of DMSO 100% and it will be applied with cotton bud for a period of 3 minutes while the child is opening his mouth and the saliva is controlled by saliva absorbent. Then the palatal probe will be performed with a dental probe in contact with the bone to estimate anesthetic effectiveness.

DRUG

Oral patches with EMLA Cream

EMLA cream 5% will be applied at a distance of 1 mm from the palatal gingival edge using an oral patch 14\*14 mm for 3 minutes and the Mouth will be closed throughout the procedure. Then the palatal probe will be performed with a dental probe in contact with the bone to estimate anesthetic effectiveness

DRUG

Micro-needle patches dissolved with EMLA Cream

EMLA cream 5% will be applied at a distance of 1 mm from the palatal gingival edge using an micro-needle patch 14\*14 mm, 0,25 micron for 3 minutes and the Mouth will be closed throughout the procedure. Then the palatal probe will be performed with a dental probe in contact with the bone to estimate anesthetic effectiveness.

Trial Locations (1)

Unknown

Damascus University, Damascus

All Listed Sponsors
lead

Damascus University

OTHER